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9th Annual Pharmaceutical Analysis Congress, will be organized around the theme “Innovations in Pharmaceutical Analysis and Quality”
Pharma Analysis 2017 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Pharma Analysis 2017
Submit your abstract to any of the mentioned tracks.
Register now for the conference by choosing an appropriate package suitable to you.
The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices, Pre formulation evaluation of pharmaceutical materials, Physical pharmacy and formulation, Research process engineering and scale-up of drug delivery systems, Drug delivery systems evaluation and quality improvement and Global standardization of pharmaceutical information
- Track 1-1Nanotechnology for enhancing bioavailability
- Track 1-2Biopharmaceutics and Pharmacokinetics
- Track 1-3Optimization techniques
- Track 1-4Methodological advancements in pharmaceutical industries
- Track 1-5Novel drug target approaches
- Track 1-6Recent advances in medical devices
Chromatography can be described as a mass transfer process involving adsorption. HPLC relies on pumps to pass a pressurized liquid and a sample mixture through a column filled with adsorbent, leading to the separation of the sample components. The active component of the column, the adsorbent, is typically a granular material made of solid particles (e.g. silica, polymers, etc.), 2–50 micrometers in size. The components of the sample mixture are separated from each other due to their different degrees of interaction with the adsorbent particles. The pressurized liquid is typically a mixture of solvents (e.g. water, acetonitrile and/or methanol) and is referred to as a "mobile phase".
- Track 2-1 Hyphenated HPLC methods
- Track 2-2 Adsorption chromatography
- Track 2-3Chip based separations
- Track 2-4Ion exchange chromatography
- Track 2-5Separation techniques in chemistry
- Track 2-6Novel techniques in chromatography
Regulatory Affairs Department is the backbone of Pharmaceutical Industry. It is the revenue generator for pharmaceutical Industry. The Regulatory Affairs department is an important part of the pharmaceutical companies. More than 15 years span is required to develop and launch a new pharmaceutical product in the market. The Regulatory Affairs Agencies explains expenditure spent on each drug annually is $850 million in US. The Indian Pharmaceutical industry is one of the fastest growing industries in India, with a compounded annual growth rate (CAGR) of over 13 % in last 5 years and it is expected to grow at a higher rate in coming 10 years India spends around $300 million, united kingdom $700 , Brazil $200 million , France $550, Italy $400 As per cabinet decision in June 2010 in Japan amended a new policy i.e., Health power strategy through “Life Innovation” and expenditure spent on each drug was $450 million
- Track 3-1Career development in regulatory affairs
- Track 3-2Regulatory strategies and developments
- Track 3-3Regulatory communications and submissions
- Track 3-4Regulatory challenges for medical devices
- Track 3-5Regulatory requirements for pharmaceuticals
- Track 3-6Biologics and Biosimilars
Quality control (QC) is a procedure or set of procedures intended to ensure that a manufactured product or performed service adheres to a defined set of quality criteria or meets the requirements of the client or customer. In developing products and services, quality assurance is any systematic process of checking to see whether a product or service being developed is meeting specified requirements. Many companies have a separate department devoted to quality assurance. A quality assurance system is said to increase customer confidence and a company's credibility, to improve work processes and efficiency, and to enable a company to better compete with others. Quality assurance was initially introduced in World War II when munitions were inspected and tested for defects after they were made. Today's quality assurance systems emphasize catching defects before they get into the final product.
- Track 4-1Quality control in pharmaceutical labs
- Track 4-2Current regulations and quality Standards
- Track 4-3 The role of quality impact assessment and effectiveness checks
- Track 4-4Contract and sterile/aseptic manufacturing
- Track 4-5Storage, distribution, and transportation
- Track 4-6Formulation development
- Track 4-7Industrial pharmacy
"Innovation." This word is at the heart of bio/pharmaceutical development and manufacturing, whether innovators are targeting a new cell line or formulation, a drug delivery target or method, an analytical or packaging approach, or a quality system. As FDA Commissioner Margaret Hamburg said in April of this year at the Boston NEHI conference on "Bridging the Innovation Gap," innovation "is an issue that is important to us all, whether you come from industry, from academia, from clinical practice, or from government." She spoke about the challenges facing R&D and product pipelines, including patent-cliff implications, stating that, "The trend lines for innovative products relative to investments in research and development are not what any of us would
- Track 5-1Regulatory Requirements for Pharmaceuticals
- Track 5-2Medico Marketing & Digital Pharma
- Track 5-3Generics and Biologics
- Track 5-4Pharma and Biotech Financial Outlook
- Track 5-5R&D Advancement and Development
- Track 5-6Clinical Pharmacy and Therapeutics
- Track 5-7Pharmaceutical Sciences
Nanotechnology is the ability to understand and control matter at the very smallest scales, from around 100 nanometers right down to the dimensions of single atoms; a nanometer is one thousand millionth of a meter or about the distance your hair grows in one second. At this scale, properties can be very different when compared to those with which we are familiar. Such radical new properties mean that nanotechnology has the potential to revolutionize our current technologies and industries, and offers many opportunities to create revolutionary new drug delivery systems, formulations for poorly soluble drugs and novel devices. The Nano scale is defined as a size range of below 1 m. Scientific findings related to micro and macro systems with functionality residing within features defined at the Nano scale are also within the scope of the journal. Manuscripts detailing the synthesis, exhaustive characterization, biological evaluation, clinical testing and/ or toxicological assessment of nanomaterial’s are of particular interest to the journals readership. Articles should be self-contained, centered around a well-founded hypothesis and should aim to showcase the pharmaceutical/ diagnostic implications of the nanotechnology approach.
- Track 6-1Pre-formulation and formulation aspects
- Track 6-2Pharmacokinetics and pharmacodynamics in drugs
- Track 6-3Drug targeting and design
- Track 6-4Nanotechnology in drug delivery
- Track 6-5Smart Drug Delivery Systems
- Track 6-6Biomaterials in Drug Delivery
- Track 6-7Vaccine drug delivery systems
- Track 6-8Medical Devices for Drug Delivery
- Track 6-9Peptides and protein drug delivery
Chromatography’ is an analytical technique commonly used for separating a mixture of chemical substances into its individual components, so that the individual components can be thoroughly analyzed. There are many types of chromatography e.g., liquid chromatography, gas chromatography, ion-exchange chromatography, affinity chromatography, but all of these employ the same basic principles. Chromatography is a separation technique that every organic chemist and biochemist is familiar with. I, myself, being an organic chemist, have routinely carried out chromatographic separations of a variety of mixture of compounds in the lab. In fact, I was leafing through my research slides and came across a pictorial representation of an actual chromatographic separation that I had carried out in the lab. I guess that picture would be a good starting point for this tutorial
- Track 7-1Adsorption chromatography
- Track 7-2Advancement and application in chromatography
- Track 7-3Special techniques in chromatography
- Track 7-4High performance liquid chromatography
- Track 7-5Gas chromatography
- Track 7-6Affinity chromatography
- Track 7-7Separation techniques in chemistry
- Track 7-8Ion exchange chromatography
- Track 7-9Partition chromatography
- Track 7-10Novel techniques in chromatography
Before a drug can be manufactured at any scale, much work goes into the actual formulation of the drug. Formulation development scientists must evaluate a compound for uniformity, stability and many other factors. After the evaluation phase, a solution must be developed to deliver the drug in its required form such as solid, semi-solid, immediate or controlled release, tablet, capsule, and many other variations. With a very small quantity of active pharmaceutical ingredients (API) or drug-able candidate molecules, Piramal Pharma Solution’s pre-formulation service can provide valuable information and expertise to guide the compounds to next steps. Our pre-formulation team has extensive experience handling a wide range of compounds and can suggest the path forward for early success.
- Track 8-1Novel drug delivery system
- Track 8-2Computer aided drug designing (CADD)
- Track 8-3Drug targeting and rational drug design
- Track 8-4Pharmacokinetics and pharmacodynamics in drugs
- Track 8-5Analytical method development and validation
- Track 8-6Drug product manufacturing
- Track 8-7Shelf life and stability studies
- Track 8-8Role of API in research and development
- Track 8-9Drug evolution process of IND, NDA & ANDA
- Track 8-10Bio markers in drug designing
In determining bioequivalence, for example, between two products such as a commercially available Brand product and a potential to-be-marketed Generic product, pharmacokinetic studies are conducted whereby each of the preparations are administered in a cross-over study to volunteer subjects, generally healthy individuals but occasionally in patients. Serum/plasma samples are obtained at regular intervals and assayed for parent drug (or occasionally metabolite) concentration. Occasionally, blood concentration levels are neither feasible nor possible to compare the two products (e.g. inhaled corticosteroids), then pharmacodynamics endpoints rather than pharmacokinetic endpoints (see below) are used for comparison. For a pharmacokinetic comparison, the plasma concentration data are used to assess key pharmacokinetic parameters such as area under the curve (AUC), peak concentration (Cmax), time to peak concentration (Tmax), and absorption lag time (tlag). Testing should be conducted at several different doses, especially when the drug displays non-linear pharmacokinetics.
- Track 9-1Clinical trials
- Track 9-2Contract research organizations
- Track 9-3Challenges in drug design and drug development
- Track 9-4Bioavailability and bioequivalence studies
- Track 9-5Nutrient bioavailability
- Track 9-6Advances in BA and BE
A separation process is a method to achieve any phenomenon that converts a mixture of chemical substance into two or more distinct product mixtures, which may be referred to as mixture. At least one of which is enriched in one or more of the mixture's constituents. In some cases, a separation may fully divide the mixture into its pure constituents. Separations differ in chemical properties or physical properties such as size, shape, mass, density, or chemical affinity, between the constituents of a mixture. They are often classified according to the particular differences they use to achieve separation. Usually there is only physical movement and no substantial chemical modification. If no single difference can be used to accomplish a desired separation, multiple operations will often be performed in combination to achieve the desired end. With a few exceptions, elements or compounds are naturally found in an impure state. Often these impure raw materials must be separated into their purified components before they can be put to productive use, making separation techniques essential for the modern industrial economy. In some cases, these separations require total purification, as in the electrolysis refining of bauxite ore for aluminum metal, but a good example of an incomplete separation technique is oil refining. Crude oil occurs naturally as a mixture of various hydrocarbons and impurities.
- Track 10-1Membrane technology in separation processes
- Track 10-2Novel separation techniques in chemistry
- Track 10-3Emerging separation technologies
- Track 10-4Advancements in sample preparation techniques
- Track 10-5Chromatography as a separation technique
- Track 10-6Hyphenated techniques
- Track 10-7Applications of separation techniques
Spectroscopy and spectrograph are terms used to refer to the measurement of radiation intensity as a function of wavelength and are often used to describe experimental spectroscopic methods. Spectral measurement devices are referred to as spectrometers, spectrophotometers, spectrographs or spectral analyzers.Daily observations of color can be related to spectroscopy. Neon lighting is a direct application of atomic spectroscopy. Neon and other noble gases have characteristic emission frequencies (colors). Neon lamps use collision of electrons with the gas to excite these emissions. Inks, dyes and paints include chemical compounds selected for their spectral characteristics in order to generate specific colors and hues. A commonly encountered molecular spectrum is that of nitrogen dioxide. Gaseous nitrogen dioxide has a characteristic red absorption feature, and this gives air polluted with nitrogen dioxide a reddish-brown color. Rayleigh scattering is a spectroscopic scattering phenomenon that accounts for the color of the sky.
- Track 11-1Applications and innovations in mass spectrometry
- Track 11-2Spectrometry in proteomics
- Track 11-3Recent advances and development in spectrometry
- Track 11-4Mass spectrometry imaging
- Track 11-5Fundamentals of spectrometry
- Track 11-6Ionization techniques
- Track 11-7Spectrometry configurations and sample preparation techniques
- Track 11-8Chromatography and high performance liquid chromatography (HPLC)
Chemists in research and development laboratories have relatively few published resources on the design and analysis of experiments. In recent years massive changes have occurred in the tools and instrumentation at their disposal, in the scale of databases linking the properties of pure materials, solutions or other mixtures to molecular structure, and in the sheer ability to collect data through automated data acquisition systems. Despite these advances, many chemists still apply only rudimentary data analysis techniques and remain unaware of the advances made in information extraction over the last decade. Design and Analysis in Chemical Research provides the means to overcome that problem. An international panel of contributors addresses the principles of design and analysis in chemical research and development, with a thoughtful, user-friendly approach. Organized in chapters dealing with major activities, this volume generates understanding through numerous examples and practical applications drawn from research and development chemistry. The authors concentrate on principles and interpretation rather than formal derivation and proof, and adopt the unifying theme that statistics and chemo metrics are essentially extensions of the logical processes used every day by chemists. Thus, they allow a greater understanding of problems more quickly and easily than purely intuitive methods.
- Track 12-1Pharmacological research chemicals in the context of drug law avoidance
- Track 12-2Processes of discovering and devising new pharmacotherapy
- Track 12-3Design and analysis in chemical research and development
- Track 12-4Chemists in research and development laboratories
- Track 12-5Relationship between regression coefficients in LVR and MLR
Aprotic solvents are nonpartisan, synthetically latent substances, for example, benzene and chloroform. They have a low dielectric consistent, don't respond with either acids or bases and in this manner don't support ionization. The way that picric corrosive gives a lacklustre arrangement in benzene which gets to be distinctly yellow on including aniline demonstrates that picric corrosive is not separated in benzene arrangement furthermore that within the sight of the base aniline it works as a corrosive, the improvement of yellow shading being because of development of the picrate particle. Since separation is not a fundamental preparatory to balance, aprotic solvents are regularly added to "ionizing" solvents to discourage solvolysis (which is practically identical to hydrolysis) of the balance item thus hone the endpoint.
- Track 13-1Physical and chemical characteristic of the drug molecule
- Track 13-2Lowry and bronsted’s theory
- Track 13-3Analysis of liquid and solid dosage forms
- Track 13-4Effects of temperature on assay
- Track 13-5Protogenic and Amphiprotic solvents
Analytical errors is essential before submit your report and results with the required level of confidence. However we should have clarity regarding accuracy and precision before we are talking pharmaceutical error. Most of us believe that these terms have same meaning but the example of arrows striking a target. Any measurement is limited by the precision of the measuring instruments and the technique and the skill of the observer. Where a measurement consists of a single reading on a simple piece of laboratory equipment, for example a burette or a thermometer, one would expect the number of variables contributing to uncertainties in that measurement to be fewer than a measurement which is the result of a multi-step process consisting of two or more weight measurements, a titration and the use of a variety of reagents.
- Track 14-1Procedure for sampling techniques
- Track 14-2Validation of pharmaceutical analysis
- Track 14-3Determinate or systematic error
- Track 14-4Indeterminate or random error
- Track 14-5Basic calculation in pharmaceutical analysis
Accuracy and precision is the key words to be determined during method validation. Both accuracy and precision determine the error of an analytical measurement. Accuracy value is the true value of the sample. Precision on the other hand, refer to the variability of measurement within a set. While general usage may be lax at times, in statistical calculations and in regulations, these two terms have different and very distinct meanings. Knowing the precise definitions and importance of each are critical to the development of a sound laboratory quality control program. These two are necessary to ensure that results are valid. In general, failure to achieve either accuracy requirement or precision requirements is sufficient to constitute a failed test or calibration.
- Track 15-1Parameters of validation
- Track 15-2Purity and management of pharma analysis
- Track 15-3Pharmaceutical chemical management
- Track 15-4Linearity and Range
The modern pharmaceutical industry follows its foundations to two sources. The first of these were nearby pharmacists that extended from their customary part circulating herbal medications, for example, morphine and quinine to discount fabricate in the mid1800s. Normal medication disclosure from plants began especially with the disconnection of morphine, pain relieving and rest instigating operator from opium, by the german pharmacist partner friedrich sertürner, who named the compound after the greek divine force of dreams, Morpheus. Multinational enterprises including merck, hoffman-la roche, burroughs-wellcome (now some portion of glaxo smith kline), abbott research facilities, eli lilly and upjohn (now some portion of pfizer) started as neighborhood pharmacist shops in the mid-1800s. By the late 1880s, german color makers had idealized the cleansing of individual natural mixes from coal tar and other mineral sources and had additionally settled simple techniques in natural concoction synthesis.
- Track 16-1Documentation of pharma industry
- Track 16-2Regulation of the quality of analytical methods
- Track 16-3Biological respond and chemical purity
- Track 16-4Thermo analytical analysis
- Track 16-5High performance liquid chromatography
Limit tests of analytical procedures is important in demonstrating that a drug substance is suitable for a particular purpose. Limit test is nothing but to identify the impurities in the substance and compare it with standard. In general, limit test is defined as quantitative or semi quantitative test designed to identify and control small quantities of impurity which is likely to be present in the substance. Limit test is generally carried out to determine the inorganic impurities present in compound. Common Limit tests characteristics include: accuracy, precision (repeatability and intermediate precision), specificity, detection limit, quantitation limit, linearity, range, and robustness. In cases such as changes in synthesis of the drug substance, changes in composition of the finished product, and changes in the analytical procedure, revalidation is necessary to ensure quality control.
- Track 17-1Stabilty of drug dosade form
- Track 17-2Tests for arsenic
- Track 17-3Tests for chloride
- Track 17-4Quantitative determinations
The safety of the drug is dependent not only on the intrinsic toxicological properties of the active ingredient, but also on the impurities and degradation products that it may contain. One of the most important considerations in the drug discovery process is safety, not only of the drug itself, but also impurities and degradation products. Impurities present in the active pharmaceutical ingredient (API) have to be identified to make sure no mutagenic or toxic substances will be administered to patients. Drug product degradation profiles need to be established to guide stable formulation and provide suitable drug shelf life assessment. The presence of impurities in active ingredients can have a significant impact on the quality, safety and efficacy of pharmaceuticals. Efforts should be made to identify and characterize all unknown impurities in the drug, due to the increasing demand of regulatory agencies to manufacture high-purity drugs. The drug impurity profile is one of the most important issues in modern pharmaceutical analysis during the process of technology development for the production of high-purity substances.
- Track 18-1Weak bases in mixed aqueous and non-aqueous media
- Track 18-2Qualitative and quantitative analysis
- Track 18-3Enantiomeric impurities
- Track 18-4Organic volatile impurities
- Track 18-5Signal impurities
For a compound to achieve a tissue, it typically should be taken into the circulation system - frequently by means of mucous surfaces like the stomach related tract (intestinal assimilation) - before being taken up by the objective cells. Elements, for example, poor compound dissolvability, gastric exhausting time, intestinal travel time, substance precariousness in the stomach, and powerlessness to saturate the intestinal divider can all diminish the degree to which a medication is ingested after oral organization. Ingestion fundamentally decides the compound's bioavailability. Drugs that ingest ineffectively when taken orally should be controlled in some less alluring way, as intravenously or by inward breath (e.g. zanamivir).
The compound should be conveyed to its effector site, regularly by means of the circulation system. From that point, the compound may disperse into muscle and organs, as a rule to contrasting degrees. After passage into the systemic flow, either by intravascular infusion or by assimilation from any of the different extracellular destinations, the medication is subjected to various appropriation forms that tend to lower its plasma fixation. Mixes start to separate when they enter the body.
- Track 19-1Bio availability of drug based on drug efficacy
- Track 19-2Non-alcoholic fatty liver disease (NAFLD)
- Track 19-3Genome-wide mRNA levels in samples
- Track 19-4Role of pharmaceutical analysis in ADME
- Track 20-1Liquid-liqid extraction
- Track 20-2Thin layer chromatography
- Track 20-3Gas liquid chromatography
- Track 20-4Size exclusion chromatography
- Track 20-5Distribution co-efficient