Biography
Prof. Peter de B. Harrington is director for the Center for Intelligent Chemical Instrumentation in Ohio University, USA. He has completed his Ph.D in chemistry from University of North Carolina and extends his eminence as professor of Chemistry and Biochemistry in Ohio University.
Research Interest
His main research focuses on Mass Spectrometry and ion mobility spectrometry, his group Centre for Intelligent Chemical Instrumentation is interested in coupling chemo metric methods with ion mobility and mass spectrometers, so that the chemo metric methods are transparent to the user and so that the instrument exhibits intelligent behaviour. An intelligent instrument furnishes user- or problem-defined information as opposed to data that must be interpreted by a scientist. His group is developing algorithms that perform real-time signal processing, modelling, and interpretation
Biography
Chenzhong Li, the principal investigator of the nanobioengineering/bioelectronics lab, in the Biomedical Engineering Department at Florida International University.Dr.Li received his M.Sc and Ph.D from Kumamoto University in Japan . Dr. Li served as a post-doctoral research associate at the university of British Columbia and as professional research associate at the University of Saskatchewan and Adnavance Technologies, Inc.
Research Interest
Dr. Li has made significant impact in the areas of clinical point-of-care diagnostics, biodefense and environmental related applications of biosensor technology, specifically, sensors incorporating whole cells and those used for disease-related biomarker analysis. His research employs the interfacing of bioengineering with cell electronics, bio-nano conjugations, functional nanomaterials, and device fabrication.
Biography
Dr. Schöneich is the Takeru Higuchi Professor for Bioanalytical Chemistry and Chair of the Department of Pharmaceutical Chemistry at The University of Kansas. He received his Diploma in Chemistry from the Free University Berlin, Germany, in 1987. Between 1987 and 1991 he worked in the Department of Radiation Chemistry at the Hahn-Meitner Institute for Nuclear Research in Berlin, Germany. He received his Ph.D. in Chemistry in 1990 from the Technical University Berlin, Germany. He joined the Department of Pharmaceutical Chemistry at The University of Kansas as a post-doctoral fellow in 1991, and as a faculty member in 1992; in 2004, he was a Visiting Professor at the ETH Zürich, Switzerland.
Research Interest
Professor Schöneich's research focusses on oxidative post-translational modifications of proteins in vitro and in vivo, and the consequences of such modifications for the development of protein therapeutics and biological systems. Oxidative post-translational modifications are generally carried out by reactive oxygen species and/or reactive nitrogen species. In vivo, such oxidative modifications accompany physiological disorders associated with biological aging or disease. Importantly, only selected proteins suffer oxidative modifications in vivo, which may be the result of chemical selectivity, protein structure, the rates of protein turnover, and/or specific protein-protein interactions. In vitro, i.e. in pharmaceutical formulations, protein oxidation presents an important stability problem. We are interested to generate a database which relates oxidation sensitivity to specific structural elements of proteins. With such a database at hand, we can potentially predict the stability of new protein products, facilitating pharmaceutical development. To achieve such a database, we are studying oxidative protein stability for proteins in (a) solution, (b) in polymeric matrices, and (c) in the solid state.
